Diethylcarbamazine citrate

Overview

Diethylcarbamazine citrate is an orally active microfilaricidal agent used originally in onchocerciasis and lymphatic filiariasis. Diethylcarbamazine citrate reduces eosinophil trafficking to the lung tissue and exerts anti-allergic effects. Diethylcarbamazine citrate reduces serum levels of leptin , TNF-α , IL-6 , MCP-1 , glucose, insulin , and triglycerides, and ameliorates insulin resistance without altering body, liver, or adipose tissue weights. Diethylcarbamazine citrate enhances reactive oxygen intermediate expression by polymorphonuclear neutrophils, increases lymphocyte proliferation, and inhibits actinomycetoma lesion development. Diethylcarbamazine citrate can be used for the researches of bronchial asthma, insulin resistance and infection .

Application

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Product Information

• Catalog No.: HY-12642
• CAS No.: 1642-54-2
• Molecular Formula: C16H29N3O8
• Molecular Weight: 391.42
• Purity: 98.01%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (6.39 mM); Clear solution
• Availability: In-stock

Source

Original product source