Kansuinine B

Overview

Kansuinine B is a natural diterpenoid compound with anti-inflammatory, anti-cancer and anti-viral activities, which can be isolated from the roots of Euphorbia kansui . Kansuinine B induces sustained ERK1/2 activation, inhibits IL-6 -induced Stat3 activation and tyrosine phosphorylation, and enhances serine phosphorylation of Stat3 . Kansuinine B negatively regulates the IL-6 signaling pathway by upregulating the expression of SOCS-3 . Kansuinine B promotes the proliferation of mouse splenic lymphocytes in vitro and stimulates rat peritoneal macrophages to produce NO . Kansuinine B can be used in studies related to liver cancer and COVID-19.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > STAT | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-126420
• CAS No.: 57685-46-8
• Molecular Formula: C38H42O14
• Molecular Weight: 722.73
• Purity: 99.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.25 mg/mL (1.73 mM); Clear solution
• Availability: In-stock

Source

Original product source