Tetromycin B

Overview

Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L , and cathepsin B , respectively. It inhibits the growth of T. brucei in vitro ( IC 50 =30.87 μM). Tetromycin B is also cytotoxic to HEK293T kidney cells and J774.1 macrophages ( IC 50 s=71.77 and 20.2 μM, respectively).

Application

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Product Information

• Catalog No.: HY-126489
• CAS No.: 180027-84-3
• Molecular Formula: C34H46O5
• Molecular Weight: 534.73
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source