LX7101

Overview

LX7101 is a potent LIM-kinase , ROCK and PKA inhibitor with IC 50 s of 24 nM, 1.6 nM, 10 nM and <1 nM for LIMK1 , LIMK2 , ROCK2 and PKA , respectively. LX7101 proves significantly selective for LIMK2 with IC 50 values of 4.3 nM and 32 nM for LIMK2 and LIMK1 at 2 μM ATP, respectively. LX7101 has the potential for ocular hypertension and associated glaucoma research.

Application

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Product Information

• Catalog No.: HY-12659
• CAS No.: 1192189-69-7
• Molecular Formula: C23H29N7O3
• Molecular Weight: 451.52
• Purity: 99.54%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 7.5 mg/mL (16.61 mM); Clear solution
• Availability: In-stock

Source

Original product source