Tizoxanide

Overview

Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC 50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells.

Application

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Product Information

• Catalog No.: HY-12687
• CAS No.: 173903-47-4
• Molecular Formula: C10H7N3O4S
• Molecular Weight: 265.25
• Purity: 99.97%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 5 mg/mL (18.85 mM); Suspended solution; Need ultrasonic and warming and heat to 60°C
• Availability: In-stock

Source

Original product source