6-OAU (GTPL5846) (6-n-octylaminouracil) is an GPR84 ( G protein-coupled receptor 84 ) agonist, with an EC 50 value of 105 nM. 6-OAU works as a chemoattractant to both PMNs and macrophages, and amplifies the proinflammatory cytokine IL-8 , shows proinflammatory function. 6-OAU also displays anti-bacterial function.
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