KH-CB20

Overview

KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1 and the closely related isoform CLK4 , with an IC 50 of 16.5 nM for CLK1 . KH-CB20 can also inhibit DYRK1A ( IC 50 =57.8 nM) and CLK3 ( IC 50 =488 nM).

Application

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Product Information

• Catalog No.: HY-12828A
• CAS No.: 1354448-60-4
• Molecular Formula: C15H13Cl2N3O2
• Molecular Weight: 338.19
• Purity: 99.80%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.39 mM); Suspended solution
• Availability: In-stock

Source

Original product source