UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 ( PAR4 ) antagonist ( IC 50 =4 nM; K d =1.4 nM). UDM-001651 shows antiplatelet potency ( IC 50 =25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP).
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Protease Activated Receptor (PAR)
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