KHK-IN-1 hydrochloride

Overview

KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase ( KHK ) inhibitor ( IC 50 =12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates ( IC 50 =400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Ketohexokinase

Product Information

• Catalog No.: HY-12841A
• CAS No.: 1303470-48-5
• Molecular Formula: C21H27ClN8S
• Molecular Weight: 459.01
• Purity: 98.47%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (4.53 mM); Clear solution
• Availability: In-stock

Source

Original product source