FD-IN-1

Overview

FD-IN-1 (Compound 12) is an orally bioavailable and selective factor D ( FD ) inhibitor with an IC 50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC 50 s of 7.7 and 6.5 µM, respectively.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Complement System

Product Information

• Catalog No.: HY-128570
• CAS No.: 1646682-14-5
• Molecular Formula: C23H23NO4
• Molecular Weight: 377.43
• Purity: 98.64%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.51 mM); Clear solution
• Availability: In-stock

Source

Original product source