Foropafant

Overview

Foropafant (SR27417) highly potent, competitive, selective and orally active antagonist of platelet-activating factor ( PAF ) receptor, with a K i value of 57 pM for [ 3 H]PAF binding, at least 5-fold lower than that of unlabeled PAF itself. Foropafant potently inhibits PAF-induced aggregation of rabbit and human platelets.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Platelet-activating Factor Receptor (PAFR)

Product Information

• Catalog No.: HY-128694
• CAS No.: 136468-36-5
• Molecular Formula: C28H40N4S
• Molecular Weight: 464.72
• Purity: 99.97%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.38 mM); Clear solution
• Availability: In-stock

Source

Original product source