Ifenprodil tartrate

Overview

Ifenprodil (NP-120) tartrate, a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors ( IC 50 =0.34 μM) over 400-fold than at NR1A/NR2A receptors ( IC 50 =146 μM). Ifenprodil tartrate is an α1 adrenergic receptor antagonist. Ifenprodil tartrate inhibits GIRK (Kir3) , reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has reliable inhibitory effects against A/H1N1 strains (EC 50 of 6.6 µM). Ifenprodil tartrate has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil tartrate can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease.

Application

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Product Information

• Catalog No.: HY-12882A
• CAS No.: 23210-58-4
• Molecular Formula: C21H27NO2.1/2C4H6O6
• Molecular Weight: 400.49
• Purity: 99.94%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1 mg/mL (2.50 mM); Clear solution
• Availability: In-stock

Source

Original product source