ML318

Overview

ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC 50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC 50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.

Application

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Product Information

• Catalog No.: HY-129123
• CAS No.: 1610516-67-0
• Molecular Formula: C14H8F4N2
• Molecular Weight: 280.22
• Purity: 99.26%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 2.5 mg/mL (8.92 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source