Lunarine is an alkaloid, which can be isolated from the seeds of kale ( Lunaria annua ). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD 50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase ( TryR ) with K i of 304 μM.
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