KMUP-1 is a xanthine derivative with vasodilator activity. KMUP-1 is a inhibitor of phosphodiesterase (PDE) and activator of soluble guanylyl cyclase (sGC) . KMUP-1 stimulates NO/sGC/cyclic GMP pathway. KMUP-1 has K + channels opening activity. KMUP-1 ameliorates ischemia-induced cardiomyocyte apoptosis . KMUP-1 can be used for cardiovascular and anti-inflammatory study.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Guanylate Cyclase | Products > Signaling Pathways > Potassium Channel
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