K-Ras ligand-Linker Conjugate 2

Overview

K-Ras ligand-Linker Conjugate 2 incorporates a ligand for K-Ras , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2 , and IAP ). K-Ras ligand-Linker Conjugate 2 can be used in the synthesis of PROTAC K-Ras Degrader-1 ( HY-129523 ), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Target Protein Ligand-Linker Conjugates

Product Information

• Catalog No.: HY-129776
• CAS No.: 2741300-61-6
• Molecular Formula: C45H58N8O7
• Molecular Weight: 822.99
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source