ALS-8112 -TP is the 5'-triphosphate metabolite of ALS-8112 ( HY-12983 ). ALS-8112 -TP is a potent, selective and competitive respiratory syncytial virus ( RSV ) RNA polymerase inhibitor, with selectivity against polymerases from host or viruses unrelated to RSV such as hepatitis C virus ( HCV ). ALS-8112 -TP can be efficiently recognized by the recombinant RSV polymerase complex, causing chain termination of RNA synthesis. ALS-8112 -TP can be used for RSV-infection research.
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