Bis-​PEG4-​NHS ester

Bis-​PEG4-​NHS ester
  • CAS No.:1314378-11-4
  • Grade:97.0%
  • Formula:C20H28N2O12
  • M.W.:488.44

Overview

Bis-PEG4-NHS ester is a crosslinking reagent and amine-reactive modulator.Bis-PEG4-NHS ester reacts with primary amine groups on liposome surfaces via amide bond formation to covalently attach dibenzylcyclooctyne groups, with a hydrophilic PEG4 spacer reducing steric hindrance for subsequent click chemistry.Bis-PEG4-NHS ester enables site-specific antibody coupling to liposome surfaces via copper-free strain-promoted alkyne-azide cycloaddition click chemistry without disrupting liposome structure in minimal organic solvent volumes.Bis-PEG4-NHS ester undergoes hydrolysis during annealing to form -COOH groups that interact with PbI and FAI to enhance perovskite structural integrity, passivate defects, and modulate nucleation kinetics to regulate crystal growth.Bis-PEG4-NHS ester enhances device efficiency and long-term stability when used as an antisolvent additive for p-i-n perovskite solar cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > ADC Linkers

Product Information

  • Catalog No.: HY-130086
  • CAS No.: 1314378-11-4
  • Molecular Formula: C20H28N2O12
  • Molecular Weight: 488.44
  • Purity: 97.0%
  • Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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