Ivacaftor-d 18 is the deuterium labeled Ivacaftor. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC 50 s of 100 nM and 25 nM, respectively.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > CFTR
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