(R,R)-PCSK9 degrader 1

Overview

(R,R)-PCSK9 degrader 1 is the isomer of PCSK9 degrader 1 ( HY-130245 ). PCSK9 degrader 1 (Compound 16) is a small molecule ligand for proprotein convertase substilisin-like/kexin type 9 ( PCSK9 ) and shows high affinity to PCSK9 with a K i of 107 nM. PCSK9 degrader 1 can involve in a protein-protein interaction with the low-density lipoprotein (LDL) receptor.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > PCSK9

Product Information

• Catalog No.: HY-130245A
• CAS No.: 2216703-12-5
• Molecular Formula: C53H69FN8O13S
• Molecular Weight: 1077.22
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source