NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC 50 of 25 nM and a K i of 33 nM, and shows almost no activity towards rat SUCNR1 . NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a K i value of 17.4 nM.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Succinate Receptor 1
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