(±)8(9)-EpETE

Overview

Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca 2+ -activated K + (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin-converting Enzyme (ACE)

Product Information

• Catalog No.: HY-130309
• CAS No.: 851378-93-3
• Molecular Formula: C20H30O3
• Molecular Weight: 318.45
• Purity: 99.9%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source