W-7

Overview

W-7 is a selective calmodulin antagonist. W-7 inhibits the Ca 2+ -calmodulin -dependent phosphodiesterase and myosin light chain kinase with IC 50 values of 28 μM and 51 μM, respectively. W-7 induces apoptosis and has antitumor and vascular relaxing activity. W-7 is a blocker of Kv4.3 and can be used for research of arrhythmias.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Calmodulin | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Myosin

Product Information

• Catalog No.: HY-130368
• CAS No.: 65595-90-6
• Molecular Formula: C16H21ClN2O2S
• Molecular Weight: 340.87
• Purity: 99.35%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.33 mM); Clear solution
• Availability: In-stock

Source

Original product source