Other grades of this product :
| 2-AMINO-5-FLUOROACETOPHENONE Basic information | | Uses |
| Product Name: | 2-AMINO-5-FLUOROACETOPHENONE | | Synonyms: | 1-(2-amino-5-fluorophenyl)ethan-1-one;1-(2-Amino-5-fluorophenyl);2-AMINO-5-FLUOROACETOPHENONE;1-(2-AMino-5-fluorophenyl)ethanone;Ethanone, 1-(2-amino-5-fluorophenyl)- | | CAS: | 2343-25-1 | | MF: | C8H8FNO | | MW: | 153.15 | | EINECS: | | Product Categories: | | Mol File: | 2343-25-1.mol |
| 2-AMINO-5-FLUOROACETOPHENONE Chemical Properties |
| Melting point | 64-65 °C | | Boiling point | 264.2±20.0 °C(Predicted) | | density | 1.201±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 2.37±0.10(Predicted) |
| 2-AMINO-5-FLUOROACETOPHENONE Usage And Synthesis |
| Uses | 1-(2-Amino-5-fluorophenyl)ethanone is a useful research chemical. | | Uses | 2-Amino-5-fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | | Synthesis | 600 g of 2-ethynyl-4-fluoroaniline and 4 L of water were added to the reaction flask, and then 476 g of hydrochloric acid (concentration: 35%) was added, and thereaction was carried out at 50 °C for 36 hours.After the reaction, the temperature is lowered to 20-25 °C, the reaction solution is adjusted to pH 8-9 with 50% sodium hydroxide solution, thetemperature is controlled to not exceed 30 °C during pH adjustment, and the filter cake is washed with 1 L of water and decompressed at 50 °C. After drying for 12 h, 622 g of pale yellow solid was obtained, yield91.4%.HPLC purity was 99.2%. |
| 2-AMINO-5-FLUOROACETOPHENONE Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye