PROTAC EED degrader-1

Overview

PROTAC EED degrader-1 is a von Hippel-Lindau -based PROTAC targeting EED with a pK D of 9.02. PROTAC EED degrader-1 is a polycomb repressive complex 2 ( PRC2 ) inhibitor ( pIC 50 =8.17) targeting the EED subunit. (Pink: EED ligand ( HY-130815 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-130637 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-130614
• CAS No.: 2639882-72-5
• Molecular Formula: C55H60FN11O8S
• Molecular Weight: 1054.20
• Purity: 99.18%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 3.75 mg/mL (3.56 mM); Clear solution
• Availability: In-stock

Source

Original product source