EGFR-IN-11

Overview

EGFR-IN-11 is a fourth-generation EGFR -tyrosine kinase inhibitor ( EGFR-TKI ) with an IC 50 of 18 nM for triple mutant EGFR L858R/T790M/C797S . EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis , and arrest cell cycle at G0/G1.

Application

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Product Information

• Catalog No.: HY-130616
• CAS No.: 2463200-44-2
• Molecular Formula: C29H35N9O2S
• Molecular Weight: 573.71
• Purity: 98.76%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (3.63 mM); Clear solution
• Availability: In-stock

Source

Original product source