Eragidomide

Overview

Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue. Eragidomide coopts the CRL4 CRBN to selectively target GSPT1 for ubiquitination and proteasomal degradation.

Application

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Product Information

• Catalog No.: HY-130800
• CAS No.: 1860875-51-9
• Molecular Formula: C22H18ClF2N3O4
• Molecular Weight: 461.85
• Purity: 99.93%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.50 mM); Clear solution
• Availability: In-stock

Source

Original product source