PF 03716556 is a potent, selective, competitive and reversible acid pump (H + ,K + -ATPase) antagonist with pIC 50 s of 6.026, 6.038 and 6.009 for porcine , canine , and human recombinant gastric H + ,K + -ATPase , respectively. PF 03716556 is inactive against other receptors, ion channels, and enzymes . PF 03716556 has the potential for gastroesophageal reflux disease research .
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Proton Pump
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