Ganciclovir triphosphate

Overview

Ganciclovir triphosphate (GCV-TP) is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus ( CMV ) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis . Ganciclovir triphosphate has an IC 50 of 0.01 μM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition.

Application

Products | Products > Disease Areas > Viral Infection | Products > Disease Areas > Cytomegalovirus Infection | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > CMV | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-131605
• CAS No.: 86761-38-8
• Molecular Formula: C9H16N5O13P3
• Molecular Weight: 495.17
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source