2-(4-FLUOROBENZYLAMINO)ETHANOL

2-(4-FLUOROBENZYLAMINO)ETHANOL
  • CAS No.:22116-33-2
Other grades of this product :
2-(4-FLUOROBENZYLAMINO)ETHANOL Basic information
Uses
Product Name:2-(4-FLUOROBENZYLAMINO)ETHANOL
Synonyms:CHEMBRDG-BB 4004526;2-(4-FLUOROBENZYLAMINO)ETHANOL;Ethanol-2-(4-(fluorophenyl)methyl)amine;2-(4-Fluorobenzyl)-Ethanolamino;Ethanol, 2-[[(4-fluorophenyl)Methyl]aMino]-;2-(4-FLUOROBENZYLAMINO)ETHANOL,98%;2-[(4-fluorobenzyl)amino]ethanol(SALTDATA: FREE);2-[(4-fluorophenyl)methylamino]ethanol
CAS:22116-33-2
MF:C9H12FNO
MW:169.2
EINECS:
Product Categories:Pharmaceutical Intermediates
Mol File:22116-33-2.mol
2-(4-FLUOROBENZYLAMINO)ETHANOL Chemical Properties
Boiling point 95-98 °C(Press: 3 Torr)
density 1.1358 g/cm3
storage temp. 2-8°C
pka14.75±0.10(Predicted)
CAS DataBase Reference22116-33-2(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
HazardClass IRRITANT
MSDS Information
2-(4-FLUOROBENZYLAMINO)ETHANOL Usage And Synthesis
Uses2-[(4-Fluorobenzyl)amino]ethanol is used in preparation of (Fluorobenzyl)aminomethylmorpholine salt and its application in preparation of mosapride citrate.
Uses2-[(4-Fluorobenzyl)amino]ethanol is used in preparation of (Fluorobenzyl)aminomethylmorpholine salt and its application in preparation of mosapride citrate.
Application2-(4-FLUOROBENZYLAMINO)ETHANOL can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
SynthesisP-fluorobenzaldehyde (24.8 g, 0.2 mol) and 2-aminoethanol (15.3 g, 0.25 mol) were added to a reaction flask containing methanol (250 ml), heated to reflux, and kept at 65 ° C for 4 h.The temperature was lowered, sodium borohydride (9.2 g 0.24 mol) was added, and the reaction was stirred, the reaction was completed, filtered, and concentrated.The fraction was collected to give 2-(4-fluorobenzylamino)ethanol as a colorless oily liquid (yield: 90.2%, purity 98.7%).
2-(4-FLUOROBENZYLAMINO)ETHANOL Preparation Products And Raw materials

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