MK-8153 is a potent, selective and orally active inhibitor of renal outer medullary potassium channel (ROMK) , with IC 50 s of 5 nM, 34 μM for ROMK electrophysiology ( EP ) and hERG EP , respectively. MK-8153 can be used as the diuretic/atriuretic.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Potassium Channel
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