2-(OCTADECYLOXY)ETHANOL

CAS No.：2136-72-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-(OCTADECYLOXY)ETHANOL Basic information

Product Name:	2-(OCTADECYLOXY)ETHANOL
Synonyms:	C18E1;ETHYLENE GLYCOL MONOOCTADECYL ETHER;2-(Octadecyloxy)ethan-1-ol;2-(Octadecyloxy)ethanol, C18E1, Octadecylglycol;3-Oxahenicosane-1-ol;2-stearyloxyethanol;2-(OCTADECYLOXY)ETHANOL;OCTADECYLGLYCOL
CAS:	2136-72-3
MF:	C20H42O2
MW:	314.55
EINECS:	218-374-0
Product Categories:
Mol File:	2136-72-3.mol

2-(OCTADECYLOXY)ETHANOL Chemical Properties

Melting point	48-53 °C
Boiling point	413.1±18.0 °C(Predicted)
density	0.867±0.06 g/cm3(Predicted)
Fp	100 °C
storage temp.	2-8°C
pka	14.42±0.10(Predicted)

Safety Information

WGK Germany	3
F	3
HazardClass	IRRITANT
HS Code	2905190098

MSDS Information

Provider	Language
SigmaAldrich	English

2-(OCTADECYLOXY)ETHANOL Usage And Synthesis

Uses

2-(Octadecyloxy)ethanol is used in preparation of fatty alcohol ethoxylates via etherification of fatty alcohol with ethylene glycol.

Synthesis

Respectively, to take propylene glycol 680mg, sodium hydrogen 2.5g added to 100 ml round bottom flask,THF was added to 10 ml of a solution and stirred for 30 minutes,Then raise the temperature to reflux for 1 hour,And then weigh the bromo-octadecane dispersed in 10 ml of THF by adding a separatory funnel and dropping into the reaction solution,After refluxing the reaction overnight. After completion of the reaction, a saturated sodium chloride solution was added,Dichloromethane extraction three times, combined extract, filter evaporated solvent, crude column chromatography separation,The second band was collected, the resulting product, 550 mg, yield 17.1%.

2-(OCTADECYLOXY)ETHANOL Preparation Products And Raw materials

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