Cinanserin (SQ 10643) is a potent and selective 5-HT2 antagonist with K i values of 41, 3500 nM for 5-HT2, 5-HT1, respectively. Cinanserin also is a SARS-CoV 3CL pro inhibitor with an K D value of 49.4, 18.2 µM for SARS-CoV 3CL pro , HCoV-229E 3CL pro , respectively. Cinanserin reduces systemic burn edema levels.
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