G140

Overview

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) , with IC 50 s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activity.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Cyclic GMP-AMP Synthase

Product Information

• Catalog No.: HY-133916
• CAS No.: 2369751-07-3
• Molecular Formula: C17H16Cl2N4O2
• Molecular Weight: 379.24
• Purity: 99.17%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.48 mM); Clear solution
• Availability: In-stock

Source

Original product source