Varespladib

Overview

Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A 2 (sPLA 2 ) inhibitor with an IC 50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC 50 s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.

Application

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Product Information

• Catalog No.: HY-13402
• CAS No.: 172732-68-2
• Molecular Formula: C21H20N2O5
• Molecular Weight: 380.39
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (6.57 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source