(Rac)-SHIN2 is a pyrazolopyran derivative and a serine hydroxymethyltransferase ( SHMT ) inhibitor. (Rac)-SHIN2 has antibacterial activity and low cytotoxicity against Hep2 cells. (Rac)-SHIN2 exerts potent antibacterial activity against both vancomycin-susceptible and vanA-type vancomycin-resistant Enterococcus.
Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Others | Products > Signaling Pathways > SHMT | Products > Signaling Pathways > Bacterial
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