TETRAISOPROPYL ORTHOSILICATE

CAS No.：1992-48-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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TETRAISOPROPYL ORTHOSILICATE Basic information

Applications

Product Name:	TETRAISOPROPYL ORTHOSILICATE
Synonyms:	TETRAKIS(ISOPROPOXY)SILANE;TETRAISOPROPOXYSILANE;TETRAISOPROPYLSILANE;Tetraisopropylsilane(Tetraisopropyl orthosilicate);TETRAISOPROPYL ORTHOSILICATE;SILICON TETRA-I-PROPOXIDE;tetrakis(1-methylethyl) orthosilicate;Tetraisopropylorthosilate
CAS:	1992-48-9
MF:	C12H28O4Si
MW:	264.43
EINECS:	217-875-1
Product Categories:	Si (Classes of Silicon Compounds);Si-O Compounds;Tetraalkoxysilanes;Crosslinkers;Crosslinking Agents;Orthosilicate
Mol File:	1992-48-9.mol

TETRAISOPROPYL ORTHOSILICATE Chemical Properties

Melting point	<0°C
Boiling point	185 °C
density	0.88
refractive index	1.3895
Fp	76°C
form	clear liquid
color	Colorless to Almost colorless
Specific Gravity	0.88
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
CAS DataBase Reference	1992-48-9(CAS DataBase Reference)
NIST Chemistry Reference	Tetraisopropoxysilane(1992-48-9)
EPA Substance Registry System	Silicic acid (H4SiO4), tetrakis(1-methylethyl) ester (1992-48-9)

Safety Information

Risk Statements	20-36/37/38
Safety Statements	26-36/37/39
RIDADR	1993
TSCA	No
HazardClass	8
PackingGroup	III

MSDS Information

TETRAISOPROPYL ORTHOSILICATE Usage And Synthesis

Applications	Tetraisopropoxysilane, the iso-propyl ester of orthosilicic acid, is a colorless clear liquid. It has the following application: As an inorganic binder for refactory fillers and pigments, like precision investment castings. As a second backup casting coating. It cures faster than silica system. May be hydrolyzed to form silicon dioxide (silica). As a binder in zinc-rich (corrosion resistant) coating. As a starting material for sol-gel process. As a crosslinking agent for silicone sealant. As a drying agent in sealing compositions. As a chemical intermediate.
Chemical Properties	Colorless transparent liquid
Uses	it is impurity of Calcitonin . Calcitonin (salmon) (C144555), is a 32-amino acid linear polypeptide hormone that is produced in thyroid in humans. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH).

TETRAISOPROPYL ORTHOSILICATE Preparation Products And Raw materials

Raw materials	Silane, dichlorobis(1-methylethoxy)--->Thiosilicic acid (H4SiO3S), O,O,O-tris(1-methylethyl) ester-->Silane, chlorotris(1-methylethoxy)--->TRIISOPROPOXYSILANE-->ISOPROPYL NITRITE-->DIPOTASSIUM TRIS(1,2-BENZENEDIOLATO-O,O')SILICATE-->Tetramethyl orthosilicate-->Isopropyl alcohol
Preparation Products	CYCLOPENTADIENYLIRON DICARBONYL DIMER

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