SB-505124 (Standard) is the analytical standard of SB-505124. This product is intended for research and analytical applications. SB-505124 is a selective inhibitor of TGF-β Receptor type I receptors ( ALK4 , ALK5 , ALK7 ), with IC50s of 129 nM and 47 nM for ALK4 , ALK5 , respectively, but it does not inhibit ALK1 , 2, 3, or 6.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TGF-β Receptor
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