BM-531 is a dual-acting agent for thromboxane receptor ( TXA2 ) antagonism and thromboxane synthase inhibition. BM-531 exerts anti-aggregatory effects on human citrated platelet-rich plasma (PRP), inhibiting Arachidonic acid ( HY-109590A )-induced aggregation with an ED 100 of 0.125 μM and U-46619 ( HY-108566 )-induced aggregation with an ED 50 of 0.482 μM. BM-531 inhibits high-K + -induced contraction of porcine uterine smooth muscle.
Products | Products > Disease Areas > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Others | Products > Signaling Pathways > Prostaglandin Receptor
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