Norfluoxetine-d 5

Norfluoxetine-d 5
  • CAS No.:1185132-92-6
  • Grade:99.98%
  • Formula:C16H12D5ClF3NO
  • M.W.:336.79

Overview

Norfluoxetine -d5 is the d 5 -labeled Norfluoxetine ( HY-135556 ). Norfluoxetine is the active metabolite of the antidepressant Fluoxetine ( HY-B0102 ); it is also a TREK-2 K 2 P potassium channel inhibitor . Norfluoxetine exhibits neuroimmunological activity, induces apoptosis in primary microglial cells, and inhibits the release of pro-inflammatory factors. Norfluoxetine inhibits high-threshold voltage-gated Ca 2+ currents in neurons with an EC 50 of 20.4 μM. Norfluoxetine can be used in research related to depression, ischemic stroke, and epilepsy.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Depression | Products > Disease Areas > Epilepsy | Products > Disease Areas > Ischemic Stroke | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Potassium Channel

Product Information

  • Catalog No.: HY-135556AS
  • CAS No.: 1185132-92-6
  • Molecular Formula: C16H12D5ClF3NO
  • Molecular Weight: 336.79
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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