NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) ( HY-125033 ) as a diphosphate form. NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent . NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus ( HCV ).
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