PSB 0777 ammonium is a potent and selective adenosine A 2A receptor full agonist with K i values of 44.4 nM, 360 nM for rat and human A 2A receptors, respectively. PSB 0777 ammonium has K i values of ≥10000 nM, 541 nM for rat and human A 1 receptors, respectively. PSB 0777 ammonium shows poor brain penetrant and perorally non-absorbable effect. PSB 0777 ammonium has the potential for inflammatory bowel disease (IBS) research research.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Adenosine Receptor
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