Ascorbyl Tetraisopalmitate

Ascorbyl Tetraisopalmitate
  • CAS No.:183476-82-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
alpha [α]D20-25~-30°
Boiling point 947.4±64.0 °C(Predicted)
density 0.928~0.941g/mL (20℃)
ActiBiso-VCT is an oil soluble vitamin C derivative. Vitamin C has many functions as a cosmetic ingredient, including brightening skin, promoting collagen synthesis and inhibiting lipid peroxidation. However, vitamin C is easy to oxidize and discolor, so it is difficult to use in cosmetics. Therefore, more stable derivatives have been developed. Ascorbyl Tetraisopalmitate (ActiBiso-VCT), Vitamin C Magnesium Phosphate (ActiBiso-MAP), Vitamin C Sodium Phosphate (Actibiso-SAP) and other water-soluble VC derivatives. Oil soluble vitamin C derivatives can be used for Ascorbyl Tetraisopalmitate. It is stable at high temperature and has good solubility in oil. Ascorbyl Tetraisopalmitate shows excellent transdermal absorption, and decomposes into free vitamin C in the skin to achieve physiological function. Ascorbyl Tetraisopalmitate can be widely used in all kinds of skin care, beauty and other cosmetics.

It has the following advantages: 
Excellent percutaneous absorption
Inhibition of tyrosinase activity and melanogenesis in cells
Reduce UV induced cell / DNA damage
Prevention of lipid peroxidation and skin aging
Good solubility in common cosmetic oils
Sod like activity
Stable for heat and oxidation
Little discoloration
Cell regeneration effect

Features: Ascorbyl Tetraisopalmitate is a more stable vitamin C derivative than its precursor. However, under certain conditions, Ascorbyl Tetraisopalmitate may change color. Please use with the same care as vitamin C. 
1. The pH range of the designed preparation process shall not be higher than 6.0. L    2. It is recommended to use chelating agent in the formula, because chelating agent is very effective in preventing discoloration. 
3. Contact with water may cause oxidation of Ascorbyl Tetraisopalmitate, so it is suggested to add a long chain polyoxyethylene surfactant stabilizing system and strengthening the mask.
4. Avoid heating for a long time.

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