L-97-1 is a A1 adenosine receptor ( A1AR ) antagonist. L-97-1 is a water-soluble small molecule compound with high affinity and high selectivity against human A1 adenosine receptors. L-97-1 works by blocking A1 adenosine receptors. In patients with asthma, adenosine is an important signaling molecule capable of causing bronchoconstriction by activating A1AR . L-97-1 reduces airway hyperreactivity (BHR) by competitively binding to A1AR , thereby alleviating or blocking adenosine-induced bronchoconstriction and inflammation.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Adenosine Receptor
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