PF-00835231 is a CoV-2 cysteine 3C-like protease (3CL pro ) inhibitor, with IC 50 s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CL pro , respectively. PF-00835231 is developed for the research of anti-SARS-CoV-2/COVID-19. PF-00835231 can inhibit cell infections and also suppress infections in animal models.
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