Rp-8-pCPT-cGMPS is a competitive inhibitor of cGMP-dependent protein kinase ( PKG ) ( K i =0.5 μM). Rp-8-pCPT-cGMPS has high lipid solubility and can more easily penetrate the cell membrane and reach sufficient concentration inside the cell to inhibit cGMP-dependent protein kinase . Rp-8-pCPT-cGMPS can be used to study the activity and function of cGMP-dependent protein kinase in platelets.
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