Pomalidomide-PEG3-azide

Overview

Pomalidomide-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. Pomalidomide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates

Product Information

• Catalog No.: HY-137538
• CAS No.: 2267306-15-8
• Molecular Formula: C21H24N6O8
• Molecular Weight: 488.45
• Purity: 98.48%
• Storage: -20°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: ≥ 5 mg/mL (10.24 mM); Clear solution
• Availability: In-stock

Source

Original product source