Tacrolimus - 13 C,d 2 (FK506- 13 C,d 2 ) is the 13 C, deuterated-labeled Tacrolimus ( HY-13756 ). Tacrolimus (FK506), a molecular glue , a macrocyclic lactone, binds to FK506 binding protein ( FKBP ) to form a complex. Tacrolimus inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.
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