4-Butylresorcinol

4-Butylresorcinol
  • CAS No.:18979-61-8

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :

Melting point 50.0 to 55.0 °C
Boiling point 166°C/7mmHg(lit.)
density 1.092±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka9.95±0.18(Predicted)
color white to pale yellow powder
InChIKeyCSHZYWUPJWVTMQ-UHFFFAOYSA-N
CAS DataBase Reference18979-61-8(CAS DataBase Reference)
4-Butylresorcinol is an efficient skin whitening and brightening agent with the following effects:            
1. Strong inhibitors of tyrosinase and peroxidase;           
2. Effective skin whitening agent and skin toner;
3. Effective whitening agent for pigmentation skin;
4. Effective against chloasma (skin with excessive pigmentation when exposed to sunlight); 
5. It has a strong protective effect on DNA damage induced by H2O2;
6. It is proved to have anti saccharification effect.

In the three processes of melanin synthesis, 4-Butylresorcinol not only has an important inhibitory effect on tyrosinase activity, but also has a synergistic effect on whitening activity.
1. Before melanin synthesis, it interferes with the synthesis and glycosylation of tyrosinase to prevent the enzyme from being absorbed by melanosome.
2. During the synthesis of melanin, it can inhibit the activity of enzyme and act as a competitive inhibitor of tyrosinase and TRP1 enzyme, reducing the formation of by-product of melanin.
3. After the synthesis of melanin, it can improve the degradation of tyrosinase, inhibit the transfer of melanosome to keratinocytes, and has the effect of light peeling due to the effect of fatty acids. This function is enhanced by the presence of fatty acids and regulates the degradation of tyrosinase.

Application: Cream, essence, essential oil system.
Added amount: 0.1-0.3%
Package: 1kg / bag
Shelf life: two years


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