alpha-Arbutin

alpha-Arbutin
  • CAS No.:84380-01-8

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :

Melting point 195-196°C
Boiling point 561.6±50.0 °C(Predicted)
density 1.556±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka10.10±0.15(Predicted)
form Solid
color White to Off-White
BRN 89675
InChIKeyBJRNKVDFDLYUGJ-ZIQFBCGOSA-N
CAS DataBase Reference84380-01-8(CAS DataBase Reference)
Alpha-Arbutin is transformed by biological enzyme. The product is a single α configuration with high purity and good stability.
The whitening mechanism of α-arbutin: the structure of arbutin and tyrosine is similar, so it has the characteristics of competitive tyrosinase. Through the direct combination of itself and tyrosinase, it competes for the binding site of dopa, inhibits the activity of tyrosine in the skin, blocks the generation of melanin, accelerates the decomposition and excretion of melanin, so as to reduce the deposition of melanin in the skin, remove the spots and freckles, and has no toxic, irritant, sensitizing and other side effects on melanin cells, and has bactericidal effect.

Product characteristics
1. Alpha-Arbutin is the most safe and effective whitening material, which is the most ideal skin whitening and freckle removing active agent in the 21st century;          
2. The whitening stability and persistence of Alpha-Arbutin can be as much as 15 times as that of β - arbutin;
3.It does not produce hydroquinone in the whole process of action, has no side effects such as irritant and sensitizing, and also has functions such as skin moistening, increasing wound, sterilization and synergistic anti-inflammatory.

Expiry Date: 2 years
Package: 1kg per aluminum foil bag; 25kg per fiber can


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